The Janus Face of Cathelicidin in Tumorigenesis
Publication in refereed journal


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摘要Cathelicidin is a host defense peptide with multiple innate immunity-related functions. Recent findings indicate that cathelicidin is frequently dysregulated in human cancers where it plays a paradoxical yet dominant role in the regulation of tumor malignancy. In this review, the regulation of malignant phenotypes by cathelicidin in relation to the activation of its receptors and intracellular signaling is discussed.
著者Wu WKK, Sung JJY, Cheng ASL, Chan FKL, Ng SSM, To KF, Wang XJ, Zhang L, Wong SH, Yu J, Cho CH
期刊名稱Current Medicinal Chemistry
出版年份2014
月份1
日期1
卷號21
期次21
出版社Bentham Science Publishers
頁次2392 - 2400
國際標準期刊號0929-8673
電子國際標準期刊號1875-533X
語言英式英語
關鍵詞Angiogenesis; apoptosis; LL-37; receptor; signaling
Web of Science 學科類別Biochemistry & Molecular Biology; BIOCHEMISTRY & MOLECULAR BIOLOGY; Chemistry, Medicinal; CHEMISTRY, MEDICINAL; Pharmacology & Pharmacy; PHARMACOLOGY & PHARMACY

上次更新時間 2021-23-01 於 01:55