Dielectric investigations on how Mg salt is dispersed in and released from polylactic acid
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AbstractComposite biomaterials made of biodegradable polylactic acid (PLA) and bioactive magnesium (Mg) salt are developed for orthopaedic implants or metal implant coatings. The releasing of Mg salt into the biological environment benefits the bone growth, while with the releasing of Mg salt and degradation of PLA there forms a porous scaffold for tissue engineering. The size and morphology of the salt and voids are adjustable with such preparation conditions as salt content, pH of casting solution, and the solidification rate, so that we can control the salt releasing and degradation rate of PLA. Dielectric spectroscopy is used to investigate the dispersive structures of Mg salt and voids in the polymer matrix and to monitor the in situ releasing of Mg salts in the simulated body fluid (SBF). The current study provides us with an orthopedic biomaterial with controllable multi-phase structures, and a tool to investigate the in vivo behaviors of biomaterials.
All Author(s) ListCao YJ, Zhu D, Ngai T, Qin L, Wu C, Shen J
Journal nameChinese Journal of Polymer Science
Year2014
Month4
Day1
Volume Number32
Issue Number4
PublisherWorld Scientific Publishing / Springer Verlag (Germany)
Pages497 - 508
ISSN0256-7679
eISSN1439-6203
LanguagesEnglish-United Kingdom
KeywordsBioactivity; Biodegradation; Dielectric spectroscopy; Inorganic-polymer composite; Orthopaedic biomaterials
Web of Science Subject CategoriesPolymer Science; POLYMER SCIENCE

Last updated on 2020-05-06 at 23:47