Genome-wide association and sequencing studies on colorectal cancer
Publication in refereed journal


Times Cited
Web of Science12WOS source URL (as at 19/10/2020) Click here for the latest count
Altmetrics Information
.

Other information
AbstractColorectal cancer is a leading cause of morbidity and mortality worldwide. Understanding its genetic mechanisms is key to improving risk prediction, prognostication and treatment. Results from genome-wide association studies have engendered a growing list of colorectal cancer susceptibility genes whereas the application of genome-wide mutational analysis has enabled the depiction of mutational landscape of colorectal cancer at high resolution. The development of novel technologies, such as metagenomic and single-cell sequencing, is expected to have positive impact on future genetic studies. However, challenges remain to address the changing epidemiology of colorectal cancer, issues on genetic testing, and clinical utilization of genomic data. (C) 2013 Elsevier Ltd. All rights reserved.
All Author(s) ListWong SH, Sung JJY, Chan FKL, To KF, Ng SSM, Wang XJ, Yu J, Wu WKK
Journal nameSeminars in Cancer Biology
Year2013
Month12
Day1
Volume Number23
Issue Number6
PublisherACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD
Pages502 - 511
ISSN1044-579X
LanguagesEnglish-United Kingdom
KeywordsColorectal cancer; GWAS; Mutation; Next-generation sequencing
Web of Science Subject CategoriesOncology; ONCOLOGY

Last updated on 2020-20-10 at 01:24