High-Resolution Profiling of Fetal DNA Clearance from Maternal Plasma by Massively Parallel Sequencing
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AbstractBACKGROUND: With the advent of massively parallel sequencing (MPS), DNA analysis can now be performed in a genomewide manner. Recent studies have demonstrated the high precision of MPS for quantifying fetal DNA in maternal plasma. In addition, paired-end sequencing can be used to determine the size of each sequenced DNA fragment. We applied MPS in a high-resolution investigation of the clearance profile of circulating fetal DNA.
All Author(s) ListYu SCY, Lee SWY, Jiang PY, Leung TY, Chan KCA, Chiu RWK, Lo YMD
Journal nameClinical Chemistry
Volume Number59
Issue Number8
PublisherAmerican Association for Clinical Chemistry
Pages1228 - 1237
LanguagesEnglish-United Kingdom
Web of Science Subject CategoriesMedical Laboratory Technology; MEDICAL LABORATORY TECHNOLOGY

Last updated on 2021-09-09 at 23:55