Thrombopoietin improved ventricular function and regulated remodeling genes in a rat model of myocardial infarction
Publication in refereed journal


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摘要Background: Thrombopoietin (TPO) protects against heart damages by doxorubicin-induced cardiomyopathy in animal models. We aimed to investigate the therapeutic efficacy of TPO for treatment of myocardial infarction (MI) in a rat model and explored the mechanisms in terms of the genome-wide transcriptional profile, TPO downstream protein signals, and bone marrow endothelial progenitor cells (EPCs).
著者Chan KYY, Zhou LG, Xiang P, Li KR, Ng PC, Wang CC, Li M, Pong NH, Tu L, Deng HY, Kong CKL, Sung RYT
期刊名稱International Journal of Cardiology
詳細描述167:2546-54
出版年份2013
月份9
日期10
卷號167
期次6
出版社Elsevier
頁次2546 - 2554
國際標準期刊號0167-5273
電子國際標準期刊號1874-1754
語言英式英語
關鍵詞Cardiac remodeling; Endothelial progenitor cells; Microarray profiling; Myocardial infarction; Thrombopoietin
Web of Science 學科類別Cardiac & Cardiovascular Systems; CARDIAC & CARDIOVASCULAR SYSTEMS; Cardiovascular System & Cardiology

上次更新時間 2020-17-09 於 01:48