White matter hyperintensities and quality of life in acute lacunar stroke
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摘要White matter hyperintensities (WMH) are common in stroke. The influence of WMH on health-related quality of life (HRQoL) following a lacunar stroke is unknown. This study evaluated the impact of WMH on HRQoL in acute lacunar stroke. A cohort of 160 patients with acute lacunar stroke admitted to the stroke unit of a university-affiliated regional hospital in Hong Kong was recruited. Three months after the index stroke, a research assistant administered the Short Form-36 (SF-36) to assess HRQoL. The severity of WMH was evaluated with magnetic resonance imaging (MRI). In univariate analysis, the severity of deep WMH (DWMH) negatively correlated with patients' vitality (VT; p < 0.05), social function (SF; p < 0.001), role-emotional (RE; p < 0.01), mental health (MH; p < 0.01), and mental component summary (MCS; p < 0.001) scores of HRQoL. DWMH was independently associated with all of the above five SF-36 scores (p < 0.05) in linear regression analysis. These findings suggest that DWMH has a significant impact on the HRQoL of stroke survivors. The importance of DWMH in the long-term HRQoL in lacunar stroke warrants further investigation.
著者Tang WK, Liang HJ, Chen YK, Ahuja AT, Chu WCW, Mok VCT, Ungvari GS, Wong KS
期刊名稱Neurological Sciences
出版年份2013
月份8
日期1
卷號34
期次8
出版社SPRINGER
頁次1347 - 1353
國際標準期刊號1590-1874
電子國際標準期刊號1590-3478
語言英式英語
關鍵詞Lacunar stroke; MRI; Quality of life; White matter hyperintensities
Web of Science 學科類別Clinical Neurology; CLINICAL NEUROLOGY; Neurosciences; NEUROSCIENCES; Neurosciences & Neurology

上次更新時間 2020-28-11 於 00:34