Effect of avian influenza A H5N1 infection on the expression of microRNA-141 in human respiratory epithelial cells
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AbstractBackground: Avian influenza remains a serious threat to human health. The consequence of human infection varies markedly among different subtypes of avian influenza viruses. In addition to viral factors, the difference in host cellular response is likely to play a critical role. This study aims at elucidating how avian influenza infection perturbs the host's miRNA regulatory pathways that may lead to adverse pathological events, such as cytokine storm, using the miRNA microarray approach.
All Author(s) ListLam WY, Yeung ACM, Ngai KLK, Li MS, To KF, Tsui SKW, Chan PKS
Journal nameBMC Microbiology
Detailed descriptionTo ORKTS: doi: 10.1186/1471-2180-13-104.
Deleted duplication (P138927) on 23-Feb-2015.
Volume Number13
PublisherBioMed Central
LanguagesEnglish-United Kingdom
KeywordsH1N1; H5N1; Hypercytokinemia; Inflammation; Influenza A virus; microRNA; Pathogenesis
Web of Science Subject CategoriesMicrobiology; MICROBIOLOGY

Last updated on 2020-28-11 at 00:31