Controversies on the treatment strategy for rectal submucosal cancer: Case series and review of the literature
Publication in refereed journal


摘要Endoscopic submucosal dissection (SD) has emerged as one of the treatment strategies for submucosal rectal cancers. The present study reviewed the clinical outcomes of patients with rectal submucosal cancer treated by ESD. This was a retrospective review of four patients who had rectal tumor treated by ESD from 2010 to 2012 with histopathology showing T1 submucosal adenocarcinoma. The mean age (SD) was 69.5 (7.33) and the male to female ratio was 3:1. There were no post-ESD complications. The mean (SD) size of the tumors was 2.93 (0.87)cm. One patient with deep resection margin involvement received laparoscopic low anterior resection. Another with deep margin involvement of <1mm refused surgery and was treated by chemoradiotherapy.There was no recurrence in all the cases with a mean follow-up duration of 461.3 (209.0) days. ESD was one of the important treatment strategies for T1sm-s rectal cancer especially when the risk of nodal metastasis was low. ESD spared the patient from colostomy when the T1 cancer was located in the lower third of the rectum. The role of adjuvant and neoadjuvant chemoradiotherapy remains controversial.
著者Chan SM, Chiu PWY, Hon SF, Lo AWI, Ng SSM
期刊名稱Digestive Endoscopy
出版社Wiley: 12 months
頁次2 - 5
關鍵詞Chemoradiotherapy; Endoscopic Submucosal Dissection; Rectal submucosal cancer
Web of Science 學科類別Gastroenterology & Hepatology; GASTROENTEROLOGY & HEPATOLOGY; Surgery; SURGERY

上次更新時間 2021-18-09 於 00:23