QUANTITATIVE ULTRASOUND FOR PREDICTING CURVE PROGRESSION IN ADOLESCENT IDIOPATHIC SCOLIOSIS: A PROSPECTIVE COHORT STUDY OF 294 CASES FOLLOWED-UP BEYOND SKELETAL MATURITY
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摘要Adolescent idiopathic scoliosis (AIS) is prevalent among adolescents and can carry significant morbidities. We evaluated the use of quantitative ultrasound (QUS) for predicting curve progression in patients with AIS. We recruited 294 girls with AIS at a mean age of 13.4 years, and they were prospectively followed beyond skeletal maturity for curve progression. We recorded 3 calcaneal QUS measurements at baseline, namely broadband ultrasound attenuation (BUA), velocity of sound (VOS), and stiffness index (SI). Logistic regression analysis indicated that SI, age, menarchal status, and Cobb angle were significant prognostic factors to be included in the final prediction model. The adjusted odds ratio of curve progression for Z-score of SI <= 0 was 2.00 (95% CI: 1.08-3.71). The area under the ROC curve was 0.831 (95% CI: 0.785-0.877). The results of this study indicate that SI was an independent and significant prognostic factor for AIS and could be considered in addition to other prognostic factors when estimating the risk for curve progression and planning treatment for patients with AIS. (E-mail: jackcheng@cuhk.edu.hk) (C) 2013 World Federation for Ultrasound in Medicine & Biology.
著者Lam TP, Hung VWY, Yeung HY, Chu WCW, Ng BKW, Lee KM, Qin L, Cheng JCY
期刊名稱Ultrasound in Medicine and Biology
出版年份2013
月份3
日期1
卷號39
期次3
出版社Elsevier
頁次381 - 387
國際標準期刊號0301-5629
電子國際標準期刊號1879-291X
語言英式英語
關鍵詞Adolescent idiopathic scoliosis; Prognosis; Quantitative ultrasound
Web of Science 學科類別Acoustics; ACOUSTICS; Radiology, Nuclear Medicine & Medical Imaging; RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

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