A novel green gelatin-agar microencapsulation system with P. urinaria as an improved anti-A. niger model
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AbstractIn this study, a novel green microencapsulation system was used to develop Phyllanthus urinaria (PU) extract containing microcapsules. Agar was used with gelatin as the wall matrix materials of microcapsules to prevent the use of toxic crosslinker formaldehyde. Microencapsulated PU extract was developed to improve the potential antifungal activities of PU water extracts. The active components and surface morphology of PU extract containing microcapsules were analyzed by liquid chromatography/mass spectrometry and scanning electron microscopy, respectively. The in vitro release study demonstrated that approximately 80% of drug was released after 120h. PU loaded microcapsules were shown to have a stronger anti-Aspergillus niger activity than the free drug. (C) 2012 Elsevier Ltd. All rights reserved.
All Author(s) ListLam PL, Kok SHL, Ho YW, Wong RSM, Cheng GYM, Cheng CH, Lam KH, Gambari R, Lee KKH, Chui CH
Journal nameCarbohydrate Polymers
Detailed descriptionTo ORKTS: doi:10.1016/j.carbpol.2012.09080
Volume Number92
Issue Number1
Pages877 - 880
LanguagesEnglish-United Kingdom
KeywordsAgar; Aspergillus niger; Gelatin; Microcapsules; Phyllanthus urinaria
Web of Science Subject CategoriesChemistry; Chemistry, Applied; CHEMISTRY, APPLIED; Chemistry, Organic; CHEMISTRY, ORGANIC; Polymer Science; POLYMER SCIENCE

Last updated on 2021-11-05 at 00:09