BIS-guided Anesthesia Decreases Postoperative Delirium and Cognitive Decline
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AbstractBackground: Previous clinical trials and animal experiments have suggested that long-lasting neurotoxicity of general anesthetics may lead to postoperative cognitive dysfunction (POCD). Brain function monitoring such as the bispectral index (BIS) facilitates anesthetic titration and has been shown to reduce anesthetic exposure. In a randomized controlled trial, we tested the effect of BIS monitoring on POCD in 921 elderly patients undergoing major noncardiac surgery.
All Author(s) ListChan MTV, Cheng BCP, Lee TMC, Gin T
Journal nameJournal of Neurosurgical Anesthesiology
Year2013
Month1
Day1
Volume Number25
Issue Number1
PublisherLIPPINCOTT WILLIAMS & WILKINS
Pages33 - 42
ISSN0898-4921
LanguagesEnglish-United Kingdom
Keywordsanesthetic toxicity; bispectral index; delirium; depth of anesthesia; postoperative cognitive dysfunction; postoperative complications
Web of Science Subject CategoriesAnesthesiology; ANESTHESIOLOGY; Clinical Neurology; CLINICAL NEUROLOGY; Neurosciences & Neurology; Surgery; SURGERY

Last updated on 2020-20-09 at 01:30