Enhanced cellular uptake and gene delivery of glioblastoma with deferoxamine-coated nanoparticle/plasmid DNA/branched polyethylenimine composites
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AbstractTernary composite nanomaterials based on deferoxamine-coated superparamagnetic iron oxide nanoparticles (8-10 nm), circular plasmid DNA (similar to 4 kb) with fluorescent/luminescent reporter group, and branched polyethylenimine (25 kDa, PDI = 2.5) were prepared and compared in terms of their efficiencies in transfecting brain tumor cells at low concentration.
All Author(s) ListLeung KCF, Chak CP, Lee SF, Lai JMY, Zhu XM, Wang YXJ, Sham KWY, Cheng CHK
Journal nameChemical Communications
Detailed descriptionTo ORKTS: doi: 10.1039/c2cc36663k
Year2013
Month1
Day1
Volume Number49
Issue Number6
PublisherRoyal Society of Chemistry
Pages549 - 551
ISSN1359-7345
eISSN1364-548X
LanguagesEnglish-United Kingdom
Web of Science Subject CategoriesChemistry; Chemistry, Multidisciplinary; CHEMISTRY, MULTIDISCIPLINARY

Last updated on 2020-30-10 at 00:32