Application of Chinese Herbal Medicines to Revitalize Adult Stem Cells for Tissue Regeneration
Publication in refereed journal


摘要It has been established in the recent several decades that adult stem cells play a crucial role in tissue renewal and regeneration. Adult stem cells locate in certain organs can differentiate into functional entities such as macrophages and bone cells. Hematopoietic stem cells (HSCs) and mesenchymal stem cells (MSCs) are two of the most important populations of adult stem cells. The application of these stem cells offers a new insight in treating various pathological conditions, through replenishing cells of specific functions by turning on or off the differentiating program within quiescent stem cell niches. Apart from that, they are also capable to travel through the circulation, migrate to injury sites and differentiate to enhance regeneration process. Recently, Chinese medicine (CM) has shown to be potential candidates to activate adult stem cells for tissue regeneration. This review summarizes our own, as well as others' findings concerning the use of Chinese herbal medicine in the regulation processes of adult stem cells differentiation and their movement in tissue repair and rejuvenation. A number of Chinese herbs are used as therapeutic agents and presumably preventive agents on metabolic disorders. In our opinion, the activation of adult stem cells self-regeneration not only provides a novel way to repair tissue damage, but also reduces the use of targeted drug that adversely altering the normal metabolism of human subjects.
著者Wong HL, Siu WS, Shum WT, Gao S, Leung PC, Ko CH
期刊名稱Chinese Journal of Integrative Medicine
出版社Springer Verlag (Germany)
頁次903 - 908
關鍵詞adult stem cell; circulating mesenchymal stem cells; hematopoietic stem cell; mesenchymal stem cell; traditional Chinese medicine
Web of Science 學科類別Integrative & Complementary Medicine; INTEGRATIVE & COMPLEMENTARY MEDICINE

上次更新時間 2021-13-10 於 00:26