Antagonist-mediated down-regulation of toll-like receptors increases the prevalence of human papillomavirus infection in systemic lupus erythematosus
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摘要Introduction: Prevalence of an abnormal Papanicolaou smear was significantly increased in lupus patients in cross-sectional studies, associated with a higher prevalence of high-risk human papillomavirus (HPV) infection. The nucleic acid-specific Toll-like receptors (TLRs) locate at the endolysosomal compartments and trigger the induction of cytokines for the innate immune response. This study evaluated whether abnormal host innate immune response in lupus patients may enhance HPV persistence.
著者Yu SL, Chan PKS, Wong CK, Szeto CC, Ho SC, So K, Yu MY, Yim SF, Cheung TH, Wong MCS, Cheung JLK, Yeung ACM, Li EK, Tam LS
期刊名稱Arthritis Research and Therapy
詳細描述2012.
出版年份2012
月份1
日期1
卷號14
期次2
出版社BioMed Central
國際標準期刊號1478-6354
電子國際標準期刊號1478-6362
語言英式英語
Web of Science 學科類別Rheumatology; RHEUMATOLOGY

上次更新時間 2020-20-10 於 01:06