Asthma and bronchodilator responsiveness are associated with polymorphic markers of ARG1, CRHR2 and chromosome 17q21
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AbstractObjective Asthma is caused by complex interactions between multiple genes. beta(2)-Agonist is the standard rescue treatment to relieve asthma symptoms and bronchoconstriction. A genetic study for spirometric parameters helps to predict the responses to this antiasthma treatment. This study investigated the relationship between asthma and bronchodilator responsiveness (BDR) and eight asthma genes.
All Author(s) ListSy HY, Ko FWS, Chu HY, Chan IHS, Wong GWK, Hui DSC, Leung TF
Journal namePharmacogenetics and Genomics
Volume Number22
Issue Number7
PublisherLippincott, Williams & Wilkins
Pages517 - 524
LanguagesEnglish-United Kingdom
Keywordsasthma; bronchodilator responsiveness; gene-gene interaction; multifactor dimensionality reduction; spirometry
Web of Science Subject CategoriesBiotechnology & Applied Microbiology; BIOTECHNOLOGY & APPLIED MICROBIOLOGY; Genetics & Heredity; GENETICS & HEREDITY; Pharmacology & Pharmacy; PHARMACOLOGY & PHARMACY

Last updated on 2021-17-05 at 01:33