Enhanced cellular uptake of aminosilane-coated superparamagnetic iron oxide nanoparticles in mammalian cell lines

Publication in refereed journal

CUHK Authors

Professor WANG Yixiang (Department of Imaging and Interventional Radiology)

Professor WAN Chao (School of Biomedical Sciences)

Professor CHENG Hon Ki (School of Biomedical Sciences)

Professor Anil Tejbhan AHUJA (Department of Imaging and Interventional Radiology)

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Digital Object Identifier (DOI)

http://dx.doi.org/10.2147/IJN.S28316

DOI for CUHK Users

http://easyaccess.lib.cuhk.edu.hk/login?url=http://dx.doi.org/10.2147/IJN.S28316

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AbstractPurpose: To compare the cellular uptake efficiency and cytotoxicity of aminosilane (SiO2-NH2)-coated superparamagnetic iron oxide (SPIO@SiO2-NH2) nanoparticles with three other types of SPIO nanoparticles coated with SiO2 (SPIO@SiO2), dextran (SPIO@dextran), or bare SPIO in mammalian cell lines.

All Author(s) ListZhu XM, Wang YXJ, Leung KCF, Lee SF, Zhao F, Wang DW, Lai JMY, Wan C, Cheng CHK, Ahuja AT

Journal nameInternational Journal of Nanomedicine

Detailed descriptionTo ORKTS: doi: 10.2147/IJN.S28316

Year2012

Month1

Day1

Volume Number7

PublisherDove Medical Press

Pages953 - 964

ISSN1176-9114

LanguagesEnglish-United Kingdom

Keywordscellular uptake; iron oxide; magnetic nanoparticles; SPIO; surface coating

Web of Science Subject CategoriesNanoscience & Nanotechnology; NANOSCIENCE & NANOTECHNOLOGY; Pharmacology & Pharmacy; PHARMACOLOGY & PHARMACY; Science & Technology - Other Topics

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