Genetically manipulated adult stem cells for wound healing
Publication in refereed journal


Times Cited
Web of Science20WOS source URL (as at 21/04/2021) Click here for the latest count
Altmetrics Information
.

Other information
AbstractNew knowledge of the signal controls and activities of adult stem cells (ASCs) involved in wound repair have led to extensive investigation of the topical delivery of biomacromolecules and multipotent stem cells to injured tissues for scar-less regeneration. The transplantation of genetically recombinant stem cells, which have roles as both therapeutics and carriers for gene delivery to wound sites, represents an attractive strategy for wound treatment. Here, we compare viral and non-viral vectors and three-dimensional scaffold-based transfection strategies in terms of their biosafety, recombinant efficiency and influence on the differentiation of ASCs, to indicate the future direction of the application of recombinant ASCs in wound treatment.
All Author(s) ListPeng LH, Fung KP, Leung PC, Gao JQ
Journal nameDrug Discovery Today
Detailed descriptionTo ORKTS: doi:10.1016/j.drudis.2011.07.009.
Year2011
Month11
Day1
Volume Number16
Issue Number21-22
PublisherELSEVIER SCI LTD
Pages957 - 966
ISSN1359-6446
LanguagesEnglish-United Kingdom
Web of Science Subject CategoriesPharmacology & Pharmacy; PHARMACOLOGY & PHARMACY

Last updated on 2021-21-04 at 23:46