Potent inhibition of human enterovirus 71 replication by type I interferon subtypes
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AbstractBackground: Enterovirus 71 (EV71) infection can induce a series of syndromes including herpangina, viraemia, hand-foot-and-mouth disease and even death. Outbreaks of EV71 infection have been reported periodically over the world and have caused a great number of casualties and a high medical expenditure. Some interferons (IFNs) have been used for the treatment of viral infections for decades; however, conventional IFNs only display mild anti-EV71 activities. No effective drug is currently available for the treatment of EV71 infection. Here, we aimed to investigate whether some IFN subtypes display potent anti-EV71 activities.
All Author(s) ListYi LN, He YQ, Chen Y, Kung HF, He ML
Journal nameAntiviral Therapy
Volume Number16
Issue Number1
Pages51 - 58
LanguagesEnglish-United Kingdom
Web of Science Subject CategoriesInfectious Diseases; INFECTIOUS DISEASES; Pharmacology & Pharmacy; PHARMACOLOGY & PHARMACY; Virology; VIROLOGY

Last updated on 2020-26-11 at 00:41