Multipathway Sequences for MR Thermometry
Publication in refereed journal

香港中文大學研究人員

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摘要MR-based thermometry is a valuable adjunct to thermal ablation therapies as it helps to determine when lethal doses are reached at the target and whether surrounding tissues are safe from damage. When the targeted lesion is mobile, MR data can further be used for motion-tracking purposes. The present work introduces pulse sequence modifications that enable significant improvements in terms of both temperature-to-noise-ratio properties and target-tracking abilities. Instead of sampling a single magnetization pathway as in typical MR thermometry sequences, the pulse-sequence design introduced here involves sampling at least one additional pathway. Image reconstruction changes associated with the proposed sampling scheme are also described. The method was implemented on two commonly used MR thermometry sequences: the gradient-echo and the interleaved echo-planar imaging sequences. Data from the extra pathway enabled temperature-to-noise-ratio improvements by up to 35%, without increasing scan time. Potentially of greater significance is that the sampled pathways featured very different contrast for blood vessels, facilitating their detection and use as internal landmarks for tracking purposes. Through improved temperature-to-noise-ratio and lesion-tracking abilities, the proposed pulse-sequence design may facilitate the use of MR-monitored thermal ablations as an effective treatment option even in mobile organs such as the liver and kidneys. Magn Reson Med 66:658-6689 2011. (C)2011 Wiley-Liss, Inc.
著者Madore B, Panych LP, Mei CS, Yuan J, Chu RX
期刊名稱Magnetic Resonance in Medicine
出版年份2011
月份9
日期1
卷號66
期次3
出版社JOHN WILEY & SONS INC
頁次658 - 668
國際標準期刊號0740-3194
語言英式英語
關鍵詞HIFU; image guided therapy; MR thermometry; PRF imaging
Web of Science 學科類別Radiology, Nuclear Medicine & Medical Imaging; RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

上次更新時間 2021-20-01 於 01:04