The prevalence of human papilloma virus in the anal region of male Chinese attendees in three public sexually transmitted disease clinics in Hong Kong
Publication in refereed journal




摘要Background and Objective: Human papilloma virus (HPV) infection is believed to be one of the primary causes of the rising trend of anal cancer. The aim of our study is to identify factors influencing the prevalence of HPV infection in anal region. Methods: This study was a cross-sectional one conducted from September 2008. Chinese male patients (with or without genital wart) attending three sexually transmitted disease clinics were consecutively invited to participate in the study on randomly chosen days between the study period. At the first visit, diseased patients and the control cases were asked to complete the questionnaire regarding the demographic data and sexual behaviors and swab specimens were collected blindly from the surface of pen-anal areas for HPV DNA detection. Results: A total of 160 men completed the study. On the basis of DNA analysis, the overall prevalence of anal HPV infection was found to be 16.9%. Of the men with anal HPV infection, 14.8% had an oncogenic HPV type. Risk factors independently associated with anal HPV were "presence of genital wart" and "Circumcision". Conclusion: The prevalence rate of anal HPV in this cross sectional study of STD attendees demonstrate that anal HPV infection is not uncommon in our locality. However, the prevalence rate oncogenic HPV type was relatively low compared with other studies. This study suggested that presence of genital wart and circumcision status might play important roles in HPV transmission in pen-anal area.
著者Leung WY, Chan PKS, Lau KH, Ho KM
期刊名稱Hong Kong Journal of Dermatology & Venereology
頁次6 - 13
關鍵詞Anal; circumcision; genital wart; human papilloma virus (infection)
Web of Science 學科類別Dermatology; DERMATOLOGY

上次更新時間 2021-14-01 於 23:33