Bone Morphogenic Protein-4 Impairs Endothelial Function Through Oxidative Stress-Dependent Cyclooxygenase-2 Upregulation Implications on Hypertension
Publication in refereed journal


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摘要Rationale: Bone morphogenic protein (BMP)4 can stimulate superoxide production and exert proinflammatory effects on the endothelium. The underlying mechanisms of how BMP4 mediates endothelial dysfunction and hypertension remain elusive.
著者Wong WT, Tian XY, Chen YC, Leung FP, Liu LM, Lee HK, Ng CF, Xu AM, Yao XQ, Vanhoutte PM, Tipoe GL, Huang Y
期刊名稱Circulation Research
出版年份2010
月份10
日期15
卷號107
期次8
出版社American Heart Association
頁次984 - 991
國際標準期刊號0009-7330
電子國際標準期刊號1524-4571
語言英式英語
關鍵詞bone morphogenic protein 4; cyclooxygenase-2; endothelial dysfunction; endothelium-dependent contractions; reactive oxygen species
Web of Science 學科類別Cardiac & Cardiovascular Systems; CARDIAC & CARDIOVASCULAR SYSTEMS; Cardiovascular System & Cardiology; Hematology; HEMATOLOGY; Peripheral Vascular Disease; PERIPHERAL VASCULAR DISEASE

上次更新時間 2021-15-04 於 23:45