Effect of Blue Light Radiation on Curcumin-Induced Cell Death of Breast Cancer Cells
Publication in refereed journal


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摘要In the present study, we have successfully set up a novel blue light source with the power density of 9 mW/cm(2) and the wavelength of 435.8 nm and then the novel light source was used to investigate the effect of light radiation on curcumin-induced cell death. The cytotoxicity was investigated 24 h after the treatment of curcumin and blue light radiation together using MTT reduction assay. Nuclear chromatin was observed using a fluorescent microscopy with Hoechst33258 staining. The results showed blue light radiation could significantly enhance the cytotoxicity of curcumin on the MCF-7 cells and apoptosis induction. These findings demonstrated that blue light radiation could enhance curcumin-induced cell death of breast cancer cells, suggesting light radiation may be an efficient enhancer of curcumin in the management of breast cancer.
著者Zeng XB, Leung AWN, Xia XS, Yu HP, Bai DQ, Xiang JY, Jiang Y, Xu CS
期刊名稱Laser Physics
出版年份2010
月份6
日期1
卷號20
期次6
出版社MAIK NAUKA/INTERPERIODICA/SPRINGER
頁次1500 - 1503
國際標準期刊號1054-660X
語言英式英語
Web of Science 學科類別Optics; OPTICS; Physics; Physics, Applied; PHYSICS, APPLIED

上次更新時間 2021-10-10 於 23:41