The Tumor Suppressor UCHL1 Forms a Complex with p53/MDM2/ARF to Promote p53 Signaling and Is Frequently Silenced in Nasopharyngeal Carcinoma
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AbstractPurpose: Nasopharyngeal carcinoma is prevalent in southern China and Southeast Asia, with distinct geographic and ethnic distribution. One candidate susceptibility locus has been identified at 4p11-14, with the associated candidate gene(s) not identified yet. This study investigated the role of ubiquitin carboxyl-terminal hydrolase L1 (UCHL1) in nasopharyngeal carcinoma pathogenesis.
All Author(s) ListLi LL, Tao Q, Jin HC, van Hasselt A, Poon FF, Wang X, Zeng MS, Jia WH, Zeng YX, Chan ATC, Cao Y
Journal nameClinical Cancer Research
Volume Number16
Issue Number11
PublisherAmerican Association for Cancer Research
Pages2949 - 2958
LanguagesEnglish-United Kingdom
Web of Science Subject CategoriesOncology; ONCOLOGY

Last updated on 2021-12-01 at 23:20