Abnormally up-regulated cystic fibrosis transmembrane conductance regulator expression and uterine fluid accumulation contribute to Chlamydia trachomatis-induced female infertility
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AbstractObjective: To investigate whether abnormal expression of cystic fibrosis transmembrane conductance regulator (CFTR), a cyclic adenosine 3':5' monophosphate (cAMP)-activated chloride channel, and uterine fluid accumulation upon Chlamydia trachomatis infection may result in implantation failure, thus contributing to C. trachomatis-induced female infertility.
All Author(s) ListHe Q, Tsang LL, Ajonuma LC, Chan HC
Journal nameFertility and Sterility
Volume Number93
Issue Number8
Pages2608 - 2614
LanguagesEnglish-United Kingdom
KeywordsChlamydia trachomatis; cystic fibrosis transmembrane conductance regulator; implantation; TNF-alpha
Web of Science Subject CategoriesObstetrics & Gynecology; OBSTETRICS & GYNECOLOGY; Reproductive Biology; REPRODUCTIVE BIOLOGY

Last updated on 2021-14-10 at 00:12