Neutrophil-specific single-cell RNA-sequencing discovers a novel smad3-dependent immunosuppressor PRDM2 for promoting NSCLC
Refereed conference paper presented and published in conference proceedings


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摘要The functional role of tumor-associated neutrophils (TAN) in cancer progression is still controversial and largely unknown. Interestingly, Smad3-deficiency markedly increases TANs population in a syngeneic lung carcinoma mouse model LLC. We hypothesize that TGF-β1/Smad3 signaling may play an important role in TAN regulation and its function.
著者J. CHUNG, T.L. Lee, K.F. To, H.Y. Lan, P.M.K. Tang
會議名稱ESMO Immuno-Oncology Virtual Congress 2020
會議開始日09.12.2020
會議完結日12.12.2020
會議地點Virtual
會議國家/地區瑞士
會議論文集題名Annals of Oncology
出版年份2020
月份12
卷號31
期次Suppl 7
出版社Elsevier Inc.
頁次S1455 - S1455
國際標準期刊號0923-7534
電子國際標準期刊號1569-8041
語言英式英語

上次更新時間 2022-15-01 於 00:37