Elderly men have much lower vertebral fracture risk than elderly women even at advanced age: the MrOS and MsOS (Hong Kong) year 14 follow-up radiology results
Publication in refereed journal

替代計量分析
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其它資訊
摘要Summary
MrOS MsOS (Hong Kong) studies year 14 follow-up shows for subjects without baseline osteoporotic vertebral deformity, women’s incident vertebral fracture (VF) rate was twice that of men. For subjects with vertebral deformity of baseline ≥ 20% height loss, counting subject, women’s incident VF rate was three times higher than that of men.

Introduction
For MrOS MsOS (Hong Kong) baseline (BL) studies, 2000 men and 2000 women ≥ 65 years were recruited during 2001 to 2003. This study presents the year 14 follow-up (FU).

Materials
Whole spine MRI was performed in 271 males (mean, 82.8 ± 3.6 years) and 150 females (mean, 82.0 ± 4.29 years). Osteoporotic vertebral deformity (OVD) classification included no OVD (grade 0), and OVDs with < 20%, 20~25%, > 25%~1/3, > 1/3~40%, > 40%~2/3, and > 2/3 height loss (grade 1~6). With an existing VD, a further height loss of ≥ 15% was a VD progression. A new incident VD was a change from grade 0 to ≥ grade 2 or to grade 1 with ≥ 10% height loss. OVD progression and new incident OVD were considered incident VF.

Results
The proportion of osteoporotic subjects only slightly increased during FU for men but doubled for women. Groupwise, OVD was not associated with back pain in men; but OVD with > 1/3 height loss was associated with back pain in women. For subjects without BL OVD, 7.9% of men and 14.6% of women had incident VF. For subjects with BL OVD of ≥ 20% height loss, men’s and women’s incident VF were 17.6% and 52.6%, respectively, counting subject and 1.68% and 7.89%, respectively, counting vertebra.

Conclusion
Elderly men with or without existing osteoporotic VD have much lower future VF risk than elderly women.
出版社接受日期20.10.2020
著者Wang Yi Xiang J, Nazmi Che-Nordin, Leung Jason C.S., Yu Blanche Wai Man, Griffith James F., Kwok Timothy C.Y.
期刊名稱Archives of Osteoporosis
出版年份2020
月份11
卷號15
文章號碼176
國際標準期刊號1862-3522
電子國際標準期刊號1862-3514
語言美式英語
關鍵詞Incidence, Osteoporosis, Progression, Spine, Vertebral fracture, Bone mineral density

上次更新時間 2021-17-09 於 00:35