The Chinese mitten crab genome provides insights into adaptive plasticity and developmental regulation
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AbstractThe infraorder Brachyura (true or short-tailed crabs) represents a successful group of marine invertebrates yet with limited genomic resources. Here we report a chromosome-anchored reference genome and transcriptomes of the Chinese mitten crab Eriocheir sinensis, a catadromous crab and invasive species with wide environmental tolerance, strong osmoregulatory capacity and high fertility. We show the expansion of specific gene families in the crab, including F-ATPase, which enhances our knowledge on the adaptive plasticity of this successful invasive species. Our analysis of spatio-temporal transcriptomes and the genome of E. sinensis and other decapods shows that brachyurization development is associated with down-regulation of Hox genes at the megalopa stage when tail shortening occurs. A better understanding of the molecular mechanism regulating sexual development is achieved by integrated analysis of multiple omics. These genomic resources significantly expand the gene repertoire of Brachyura, and provide insights into the biology of this group, and Crustacea in general.
All Author(s) ListZhaoxia Cui, Yuan Liu, Jianbo Yuan, Xiaojun Zhang, Tomer Ventura, Ka Yan Ma, Shuai Sun, Chengwen Song, Dongliang Zhan, Yanan Yang, Hourong Liu, Guangyi Fan, Qingle Cai, Jing Du, Jing Qin, Chengcheng Shi, Shijie Hao, Quinn P. Fitzgibbon, Gregory G. Smith, Jianhai Xiang, Tin-Yam Chan, Min Hui, Chenchang Bao, Fuhua Li, Ka Hou Chu
Journal nameNature Communications
Year2021
Month4
Volume Number12
Issue Number1
PublisherNature Publishing Group
Article number2395
ISSN2041-1723
LanguagesEnglish-United Kingdom

Last updated on 2021-26-09 at 02:09