Federated deep learning for detecting COVID-19 lung abnormalities in CT: a privacy-preserving multinational validation study
Publication in refereed journal


摘要Data privacy mechanisms are essential for rapidly scaling medical training databases to capture the heterogeneity of patient data distributions toward robust and generalizable machine learning systems. In the current COVID-19 pandemic, a major focus of artificial intelligence (AI) is interpreting chest CT, which can be readily used in the assessment and management of the disease. This paper demonstrates the feasibility of a federated learning method for detecting COVID-19 related CT abnormalities with external validation on patients from a multinational study. We recruited 132 patients from seven multinational different centers, with three internal hospitals from Hong Kong for training and testing, and four external, independent datasets from Mainland China and Germany, for validating model generalizability. We also conducted case studies on longitudinal scans for automated estimation of lesion burden for hospitalized COVID-19 patients. We explore the federated learning algorithms to develop a privacy-preserving AI model for COVID-19 medical image diagnosis with good generalization capability on unseen multinational datasets. Federated learning could provide an effective mechanism during pandemics to rapidly develop clinically useful AI across institutions and countries overcoming the burden of central aggregation of large amounts of sensitive data.
著者Qi Dou, Tiffany Y. So, Meirui Jiang, Qande Liu, Varut Vardhanabhuti, Georgios Kaissis, Zeju Li, Weixin Si, Heather H.C. Lee, Kevin Yu, Zuxin Feng, Li Dong, Egon Burian, Friderike Jungmann, Rickmer Braren, Marcus Makowski, Bernhard Kainz, Daniel Rueckert, Ben Glocker, Simon C.H. Yu, Pheng Ann Heng
期刊名稱NPJ Digital Medicine
出版社Nature Research
關鍵詞COVID-19, lung, abnormalities

上次更新時間 2021-02-05 於 00:31