Guidelines for clinical diagnosis and treatment of osteonecrosis of the femoral head in adults (2019 version)
Publication in policy or professional journal

香港中文大學研究人員
替代計量分析
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其它資訊
摘要Osteonecrosis of the femoral head (ONFH) is a common and refractory disease in orthopaedic clinics. The number of patients with ONFH is increasing worldwide every year. There are an estimated 8.12 million patients with nontraumatic osteonecrosis in China alone. Treatment of nontraumatic osteonecrosis has always been a clinical challenge for orthopaedic surgeons. To further standardize diagnosis and treatment of ONFH, these guidelines provide not only basic diagnosis, treatment, and evaluation systems for ONFH but also expert advice and standards in many aspects, including epidemiology, aetiology, diagnostic criteria, pathological staging, prevention and treatment options, and postoperative rehabilitation. The aetiological factors of ONFH can currently be divided into two major categories: traumatic and nontraumatic; however, the specific pathological mechanism of ONFH is not completely clear. Currently, the staging system of ONFH formulated by the Association Research Circulation Osseous is widely used in clinical practice. Based on the changes in the intraosseous blood supply at different stages, the corresponding nonsurgical and surgical treatments are recommended, and when there are risk factors for possible ONFH, certain preventive measures to avoid the occurrence of osteonecrosis are recommended. These guidelines provide brief classification criteria and treatment regimen for osteonecrosis. Specification of the aetiology, treatment plan based on comprehensive consideration of the different stages of osteonecrosis, hip function, age, and occupation of the patients are important steps in diagnosis and developing treatment strategies.

Translational potential of this article
New advances in the epidemiology, etiology, pathophysiology, imaging, diagnosis and treatment of ONFH have been renewed in this revision. This guideline can be used for reference by orthopedic professionals and researchers, and for standardized diagnosis and treatment management under the clinical guidance, which is conducive to the prevention, treatment and further research of ONFH, improving the diagnosis and treatment level, making patients' symptoms under good control, and improving their quality of life.
出版社接受日期06.01.2020
著者Dewei Zhao, Feng Zhang, Benjie Wang, Baoyi Liu, Lu Li, Shinyoon Kim, Stuart B Goodman, Philipe Hernigou, Quanjun Cui, William C Lineaweaver, Jiake Xu, Wolf R Drescher, Ling Qin
期刊名稱Journal of Orthopaedic Translation
出版年份2020
月份3
卷號21
出版社Elsevier
頁次100 - 110
國際標準期刊號2214-031X
語言美式英語
關鍵詞Diagnosis, Guideline, Osteonecrosis of the femoral head, treatment

上次更新時間 2021-17-09 於 00:19