Life Functioning in Chinese Survivors of Childhood Cancer in Hong Kong
Publication in refereed journal
Officially Accepted for Publication


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AbstractBackground
Evidence on self-care ability and occupational outcomes in Chinese survivors of childhood cancer is clearly lacking. This study aims to identify clinical and behavioral factors associated with poor life functioning in this population.

Methods
This was a cross-sectional study conducted at an ambulatory clinic of a public hospital in Hong Kong. Licensed occupational therapists administered the Life Functioning Assessment Inventory on survivors diagnosed with cancer <19 years old and ≥5 years post-diagnosis. Survivors’ career development self-efficacy, subjective happiness and motivation were evaluated using structured questionnaires. Clinical information was obtained from medical records. Multivariable linear regression was used to evaluate factors associated with life functioning outcomes, adjusting for clinically relevant variables.

Results
Eighty survivors were recruited (58.7% male; age at diagnosis: 6.7 [SD=4.8] years; age at evaluation: 24.4 [SD=6.5] years). As compared to survivors of leukemia, survivors of brain tumor performed worse in social functioning (β=-0.79, SE=0.36; p=0.034). Survivors who had been treated with cranial radiation also had lower worker life functioning than those who had not (β=-0.91, SE=0.031; p=0.021). Higher activity motivation was significantly associated with better leisure functioning (β=0.086, SE=0.03; p=0.008), social functioning (β=0.036, SE=0.02; p=0.036), and career development self-efficacy (β=1.04, SE=0.26; p<0.0001).

Conclusion
Survivors of brain tumors and survivors who were treated with radiation have poorer life functioning, particularly in social and work domains. Future work includes validating the study findings in a larger cohort of survivors in Hong Kong. Addressing modifiable behavioral factors include motivating survivors to engage in meaningful activities that contribute to self-care and participation in society, as well as providing at-risk survivors with ongoing support from community vocational services.
Acceptance Date03/06/2020
All Author(s) ListHellen Yang, Sanne Fong, Phoebe Chan, Alice Cheung, Liwen Peng, Jiaqi Yan, Yin Ting Cheung, Chi-Kong Li
Journal nameJournal of Adolescent and Young Adult Oncology
Year2020
ISSN2156-5333
eISSN2156-535X
LanguagesEnglish-United States
KeywordsChildhood cancer, survivorship, vocational outcomes, life functioning, occupational outcomes

Last updated on 2020-23-11 at 23:48