Patient-derived tumor organoid predicts drugs response in glioblastoma: A step forward in personalized cancer therapy?
Publication in refereed journal


引用次數
Scopus ( 14/10/2020)
替代計量分析
.

其它資訊
摘要Despite significant medical advances, glioblastoma multiforme (GBM) remains a formidable therapeutic challenge. Advent of targeted capture sequencing and patients-derived organoid cultures may hold the key to scientifically sound individualized treatment approaches. We report on our initial experience of using the combination of these two technologies to create a tailored approach of systemic therapies for a patient with GBM, which challenges the conventional treatment paradigm, as well as specifically highlighting the complexities of such an approach and the potential for a more favorable treatment outcome.
出版社接受日期20.04.2020
著者Herbert HF LOONG, Alissa M WONG, Danny TM CHAN, Maggie SH CHEUNG, Chit CHOW, Xiaofan DING, Aden KY CHAN, Paul A JOHNSTON, James YW LAU, Wai Sang POON, Nathalie WONG
期刊名稱Journal of Clinical Neuroscience
出版年份2020
月份8
卷號78
出版社Elsevier Ltd
頁次400 - 402
國際標準期刊號0967-5868
電子國際標準期刊號1532-2653
語言英式英語
關鍵詞Cancer organoid, Glioblastoma, Targeted therapy, Capture sequencing

上次更新時間 2020-15-10 於 00:28