LINC01133: an emerging tumor-associated long non-coding RNA in tumor and osteosarcoma
Publication in refereed journal


引用次數
Scopus ( 16/11/2020)
替代計量分析
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其它資訊
摘要Emerging evidence suggested that long non-coding RNAs (lncRNAs) play pivotal roles in tumorigenesis. LINC01133 is a newly identified lncRNA first discovered as an oncogene in lung squamous cell carcinoma. Subsequent studies further demonstrated this lncRNA was deregulated in a wide spectrum of tumors, including colorectal, gastric, lung, and pancreatic ductal adenocarcinoma as well as osteosarcoma and hepatocellular carcinoma. Intriguingly, this lncRNA exerted oncogenic or tumor-suppressive action in a tissue-dependent manner. This review sought to summarize our current understanding concerning the deregulation of LINC01133 in human tumors in relation to its molecular mechanisms and cellular functions. The clinical utilization of LINC01133 as a potential prognostic biomarker and a treatment target is also discussed.
出版社接受日期05.06.2020
著者Li Z, Xu D, Chen X, Li S, Chan MTV, Wu WKK
期刊名稱Environmental Science and Pollution Research
出版年份2020
月份9
卷號27
期次26
出版社Springer
頁次32467 - 32473
國際標準期刊號0944-1344
電子國際標準期刊號1614-7499
語言英式英語
關鍵詞Long non-coding RNAs . lncRNAs . LINC01133 . Osteosarcoma

上次更新時間 2020-17-11 於 00:11