Acupuncture for Poststroke Dysphagia: A Pilot, Nonrandomized, Self-Controlled Trial
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Scopus ( 25/10/2020)
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其它資訊
摘要Objective. To evaluate the effectiveness and safety of acupuncture treatment for dysphagia as a complication of stroke. Methods and Design. /is is a multicenter, pragmatic, nonrandomized, self-controlled clinical trial. A total of 39 patients were recruited from several Chinese medicine outpatient clinics and hospital-affiliated speech therapy outpatient clinics in Hong Kong. 26 patients completed all the 24 sessions of acupuncture treatment within two months, and only 12 of them were used as self-control. For the self-control group, the retrospective clinical data was taken from the electronic patient records with patient consent. /e descriptive swallowing function data were converted into the quantitative Royal Brisbane Hospital Outcome Measure for Swallowing (RBHOMS) scores by two registered
speech therapists through a validation process. And the data were validated by reaching consensus between the two speech therapists. All subjects underwent a baseline assessment before commencement of treatment, and outcome assessments were conducted upon the completion of treatment. /e primary outcome measure is the RBHOMS score, which is a swallowing disability rating scale for monitoring difficulties in daily swallowing function. Secondary outcome measures include the Chinese version of the Swallow Quality-of-Life Questionnaire and adverse events. All the primary and secondary outcomes were assessed at baseline as well as at the end of acupuncture treatment (month 2). Results. A total of 39 participants aged 46 to 89 years were enrolled in the study, and the male-to-female ratio was 15 :11. /e mean baseline RBHOMS score of all 39 participants was 5.92±2.23. /e mean retrospective RBHOMS score of the 12 subjects who were used as self-control was 5.67±1.72 before enrollment, while the mean RBHOMS score of the 26 participants who completed all the 24 sessions of treatment was 6.92±2.07. /ere were statistically significant differences between theRBHOMSscore at the completion of treatment and baseline (p =0.006), and retrospective data (p =0.042). Moreover, a significant difference was also found in terms of swallow quality-of-life score before and after acupuncture treatment (p < 0.01). Conclusions. /is pilot study provides preliminary evidence for the effectiveness of acupuncture for poststroke dysphagia./efindings from this trial can be used as a foundation for future full-scale randomized controlled clinical trials to assess the efficacy and safety of acupuncture for poststroke dysphagia. Ethics and Dissemination. /e ethical approval of the clinical research study was granted by the Research Ethics Committee of both New Territories East and West Cluster of Hong Kong. Written informed consent was obtained from all participants, and the study was undertaken according to the ICH-GCP Guidelines. Trial Registration. /is trial is registered with ChiCTR-TRC-12002621 and the registration date is 2012-10-26.
出版社接受日期20.04.2020
著者Yu Tat Chan, Hong Wei Zhang, Wai Zhu Sun, Kevin Ka Hang Or, Yuan-Qi Guo, Min Chen, Guan-Yi Wu, Guang-Yao Xu, Connie Leung, Sylvia Tam, Francis Chun-keung Mok, Yiu Keung Kwan, Eddie Chow, Joshua Kam Wo Mak, Angus Chun-Kwok Chu, Kathy Lee, Thomas Law, Rita Wai Ming Wong, Zhi-Xiu Lin
期刊名稱Evidence-Based Complementary and Alternative Medicine
出版年份2020
月份5
日期12
卷號2020
出版社Hindawi
出版地United Kingdom
文章號碼4689296
國際標準期刊號1741-427X
語言美式英語
關鍵詞Acupuncture, Poststroke Dysphagia, Pok Oi Hospital, speech therapy

上次更新時間 2020-26-10 於 00:10