Indoor Incense Burning Impacts Cognitive Functions and Brain Functional Connectivity in Community Older Adults
Publication in refereed journal

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其它資訊
摘要To investigate (1) the effects of indoor incense burning upon cognition over 3 years; (2) the associations between indoor incense burning with the brain’s structure and functional connectivity of the default mode network (DMN); and (3) the interactions between indoor incense burning and vascular disease markers upon cognitive functions. Community older adults without stroke or dementia were recruited (n = 515). Indoor incense use was self-reported as having burnt incense at home ≥ weekly basis over the past 5 years. Detailed neuropsychological battery was administered at baseline (n = 227) and the Montreal Cognitive Assessment at baseline and year 3 (n = 515). MRI structural measures and functional connectivity of the DMN were recorded at baseline. Demographic and vascular risk factors and levels of outdoor pollutants were treated as covariates. Indoor incense burning was associated with reduced performance across multiple cognitive domains at baseline and year 3 as well as decreased connectivity
in the DMN. It interacted with diabetes mellitus, hyperlipidemia and white matter hyperintensities to predict poorer cognitive performance. Indoor incense burning is (1) associated with poorer cognitive performance over 3 years; (2) related to decreased brain connectivity; and (3) it interacts with vascular disease to predispose poor cognitive performance.
著者Wong A, Lou W, Ho KF, Yiu BK, Lin S, Chu WC, Abrigo J, Lee D, Lam BY, Au LW, Soo YO, Lau AY, Kwok TC, Leung TW, Lam LC, Ho K, Mok VC.
期刊名稱Scientific Reports
出版年份2020
月份4
卷號10
期次1
出版社Nature Research
文章號碼7090
國際標準期刊號2045-2322
電子國際標準期刊號2045-2322
語言美式英語
關鍵詞DEFAULT MODE NETWORK, FINE PARTICULATE MATTER, AIR-POLLUTION, ALZHEIMERS-DISEASE, MAJOR ROADS, EXPOSURE

上次更新時間 2020-26-11 於 00:08