Real-Time Monitoring of the Effects of Personal Temperature Exposure on the Blood Oxygen Saturation Level in Elderly People with and without Chronic Obstructive Pulmonary Disease: A Panel Study in Hong Kong
Publication in refereed journal


摘要Few studies have investigated the short-term effect of personal temperature exposure on blood oxygen saturation (SpO2). We conducted this longitudinal panel study with real-time monitoring of SpO2 and environmental exposure for 3 continuous days for 20 patients with chronic obstructive pulmonary disease (COPD) and 20 healthy volunteers in Hong Kong, to explore the time course (from minutes to hours) of change in SpO2 in response to temperature in elderly people. We employed generalized additive mixed model to evaluate the acute effects of personal temperature exposure on changes in SpO2 and risk of oxygen desaturation while adjusting for seasonality, environmental co-exposures, and personal characteristics. We observed a concurrent decline in SpO2 by 0.27% (95% confidence interval [CI]: 0.22%–0.32%) and an increase in the risk of oxygen desaturation by an OR of 1.14 (95% CI: 1.10–1.18) associated with a 1oC increase in personal temperature, and the association lasted over several hours. Results showed that the decline in SpO2 in elderly people was associated with an increase in personal temperature exposure within minutes to hours, particularly in women and male patients with COPD. Temperature-induced oxygen desaturation may play a pivotal role in COPD exacerbation.
著者Qiu H, Xia X, Man CL, Ko FWS, Yim SHL, Kwok TCY, Ho KF
期刊名稱Environmental Science and Technology
出版社American Chemical Society
頁次6869 - 6877
關鍵詞Blood oxygen saturation, COPD, Personal temperature exposure, Real-time monitoring

上次更新時間 2020-26-10 於 00:03