Choice of ANesthesia for EndoVAScular Treatment of Acute Ischemic Stroke (CANVAS): Results of the CANVAS Pilot Randomized Controlled Trial
Publication in refereed journal

香港中文大學研究人員

引用次數
Scopus ( 16/11/2020)
替代計量分析
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其它資訊
摘要Background:
The effect of choice of anesthesia on clinical outcome for endovascular treatment (EVT) in patients with acute ischemic stroke (AIS) remains unclear.

Methods:
We conducted a pilot trial of 43 patients with acute anterior circulation ischemic stroke having EVT. Patients were randomly allocated to receive general anesthesia or conscious sedation. We documented the rate of recruitment and rate of conversion from conscious sedation to general anesthesia. In addition, we recorded the change in National Institute of Health stroke scale (NIHSS) on day 7, the rate of successful reperfusion and measured neurological function by certified researchers using modified Rankin Score (mRS 0 to 2) at 90 days.

Results:
The recruitment rate was 31.4% and majority of patients were excluded because of delay in hospital presentation and posterior circulation stroke. The rate of conversion from conscious sedation to general anesthesia was 18.2%. This was primarily related to excessive sedation and uncontrolled movement. Change in NIHSS score, rate of successful reperfusion and functional recovery were similar between groups.

Conclusions:
It was feasible to randomize AIS patients receiving either general anesthesia or conscious sedation for EVT.
著者Sun J, Liang F, Wu Y, Zhao Y, Miao Z, Zhang L, Gelb AW, Chan MTV, Peng Y, Han R, CANVAS Pilot Trial Investigators
期刊名稱Journal of Neurosurgical Aneshtesiology
出版年份2020
月份1
卷號32
期次1
出版社Lippincott Williams and Wilkins
頁次41 - 47
國際標準期刊號0898-4921
電子國際標準期刊號1537-1921
語言英式英語

上次更新時間 2020-16-11 於 23:51