Beneficial Effects of Dietary Polyphenols on High-Fat Diet-Induced Obesity Linking with Modulation of Gut Microbiota
Publication in refereed journal

香港中文大學研究人員
替代計量分析
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其它資訊
摘要Obesity is caused by an imbalance of energy intake and expenditure. It is characterized by a higher accumulation of body fat with a chronic low-grade inflammation. Many reports have shown that gut microbiota in the host plays a pivotal role in mediating the interaction between consumption of a high-fat diet (HFD) and onset of obesity. Accumulative evidence has suggested that the changes in the composition of gut microbiota may affect the host’s energy homeostasis, systemic inflammation, lipid metabolism, and insulin sensitivity. As one of the major components in human diet, polyphenols have demonstrated to be capable of modulating the composition of gut microbiota and reducing the HFD-induced obesity. The present review summarizes the findings of recent studies on dietary polyphenols regarding their metabolism and interaction with bacteria in the intestine as well as the underlying mechanisms by which they modulate the gut microbiota and alleviate the HFD-induced obesity.
出版社接受日期12.12.2019
著者Jianhui Liu, Zouyan He, Ning Ma, Zhen-Yu Chen
期刊名稱Journal of Agricultural and Food Chemistry
出版年份2020
月份1
日期8
卷號68
期次1
頁次33 - 47
國際標準期刊號0021-8561
電子國際標準期刊號1520-5118
語言美式英語
關鍵詞gut microbiota, high-fat diet, inflammation, obesity, polyphenols

上次更新時間 2020-29-07 於 23:52