Age-and Gender-related Normative Value of Whole-body Sagittal Alignment Based on 584 Asymptomatic Chinese Adult Population from Age 20 to 89
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摘要Study Design. A cross-sectional radiographic study. Objectives. The aim of this study was to establish the age-and sex-related normative values of whole-body sagittal alignment in asymptomatic Chinese adult population, and to investigate the changes and possible associated compensation mechanisms across age groups. Summary of Background Data. Previous studies have reported normative data for sagittal spinal alignment in asymptomatic adults. However, there was a lack of comprehensive investigation on age-and sex-related normative values of whole-body sagittal alignment. Methods. A total of 584 asymptomatic Chinese adults aged 20 to 89 years were recruited. Subjects were grouped according to age and sex. Whole-body standing radiographs were acquired for evaluating sagittal alignment from spine to lower limb. Comparisons of sagittal parameters between sex in different age groups were performed by independent t test. Pearson correlation analysis was used to determine relationships between each parameter. Results. Mean values of each sagittal parameter were presented based on age and sex. Thoracic kyphosis showed steady increasing trend while lumbar lordosis gradual decrease in both sexes. Pelvic tilt (PT) in males is greater than in females across all age groups with age-related gradual increase. There were significant differences between males and females from 20 to 60 years in terms of KneeFlex angle (KA) and AnkleFlex angle, but the differences were not significant after 60s. T1 pelvic angle (TPA) was significantly correlated with spinal, pelvic and lower-limb alignment. The older group (≥50 years) had a stronger correlation of TPA with PT and KA, whereas the younger (<50 years) had stronger correlation with TK. Conclusion. This study presented a comprehensive study of whole-body sagittal alignment based on a large asymptomatic population, which could serve as an age-and sex-specific reference value for spine surgeons when planning for correction surgery. Age can influence the recruitment of compensation mechanism that involves more pelvic and lower limb mechanisms for elderly people.Level of Evidence: 3. © 2019 Wolters Kluwer Health, Inc. Unauthorized reproduction of this article is prohibited.
著者Hu Z, Man GCW, Yeung KH, Cheung WH, Chu WCW, Law SW, Lam TP, Zhu Z, Qiu Y, Cheng JCY.
期刊名稱Spine
詳細描述Epub ahead of print
出版年份2020
月份1
日期15
卷號45
期次2
出版社Lippincott, Williams & Wilkins
頁次79 - 87
國際標準期刊號0362-2436
語言美式英語
關鍵詞Sagittal alignment, adult spinal deformity, normative value, whole-body sagittal alignment

上次更新時間 2020-09-07 於 00:58