Air pollution exposure associates with increased risk of neonatal jaundice
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AbstractClinical experience suggests increased incidences of neonatal jaundice when air quality worsens, yet no studies have quantified this relationship. Here we reports investigations in 25,782 newborns showing an increase in newborn's bilirubin levels, the indicator of neonatal jaundice risk, by 0.076 (95% CI: 0.027-0.125), 0.029 (0.014-0.044) and 0.009 (95% CI: 0.002-0.016) mg/dL per mu g/m(3) for PM2.5 exposure in the concentration ranges of 10-35, 35-75 and 75-200 mu g/m(3), respectively. The response is 0.094 (0.077-0.111) and 0.161 (0.07-0.252) mg/dL per mu g/m(3) for SO2 exposure at 10-15 and above 15 mu g/m(3), respectively, and 0.351 (0.314-0.388) mg/dL per mg/m(3) for CO exposure. Bilirubin levels increase linearly with exposure time between 0 and 48 h. Positive relationship between maternal exposure and newborn bilirubin level is also quantitated. The jaundice-pollution relationship is not affected by top-of-atmosphere incident solar irradiance and atmospheric visibility. Improving air quality may therefore be key to lowering the neonatal jaundice risk.
Acceptance Date09/07/2019
All Author(s) ListZhang LQ, Liu WW, Hou K, Lin JT, Song CQ, Zhou CH, Huang B, Tong XH, Wang JF, Rhine W, Jiao Y, Wang ZW, Ni RJ, Liu MY, Zhang L, Wang ZY, Wang YB, Li XG, Liu SH, Wang YH
Journal nameNature Communications
Year2019
Month8
Day20
Volume Number10
PublisherNature Publishing Group
Place of PublicationLondon
Article number3741
ISSN2041-1723
LanguagesEnglish-United Kingdom
Web of Science Subject CategoriesMultidisciplinary Sciences;Science & Technology - Other Topics

Last updated on 2020-19-10 at 00:36