Effects of REM sleep during a daytime nap on emotional perception in individuals with and without depression
Publication in refereed journal

香港中文大學研究人員
替代計量分析
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其它資訊
摘要Background
It has been theoretically proposed that alteration in sleep physiology may contribute to the development of biased emotional processing featured in depression. The current study investigated the role of sleep and especially REM in modulating perception of emotional faces in depressed versus non-depressed individuals using a napping paradigm.

Methods
Forty-six individuals with major depressive disorder and 66 age- and education-matched healthy controls completed an emotional face perception task before and after random assignment to one of the three intention-to-treat (ITT) conditions, namely 30-min-nap, 90-min-nap and wake. To delineate the effects of REM, as-treated (30-min-nap, 90-min-REM-nap, 90-min-noREM-nap and wake) analyses were also conducted.

Results
Repeated measures multivariate analysis of covariance (MANCOVA) showed a significant Time *Group *Condition interaction on angry faces for both analyses of ITT (p = .017) and AT (p = .027). Pairwise comparison with Bonferroni corrections revealed a significant increase in the intensity rating of angry faces only after 90-min-REM-nap in the depressed group. Correlational analyses convergingly showed that the increase of intensity rating of angry faces was associated with the proportion of REM sleep in the depressed group, p = .035.

Limitations
The observed effect of REM sleep during daytime napping may not represent the effect of nighttime REM sleep in depression.

Conclusions
We provide the first evidence of the association of daytime sleep, particularly REM sleep, with a more negative perception of angry faces exclusively in individuals with depression. The differentiated impact of sleep observed may contribute to the development of altered emotional processing in depression.
出版社接受日期11.09.2019
著者Lau EYY, Lau KNT, Chan CS, Tseng CH, Lam YC, Tse DM, Cheng WY, Chung KF, Wing YK
期刊名稱Journal of Affective Disorders
出版年份2020
月份1
日期1
卷號260
頁次687 - 694
國際標準期刊號0165-0327
語言美式英語
關鍵詞Sleep; Napping; REM sleep; Emotional processing; Emotional perception; Depression

上次更新時間 2020-11-08 於 00:37