A Novel DPP4/CD32b/NF-kB Circuit is Essential for C-Reactive Protein-Driven Type-2 Diabetic Nephropathy
Refereed conference paper presented and published in conference proceedings

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AbstractDiabetic nephropathy (DN) is one of the major causes of end-stage renal disease (ESRD), but treatment remains ineffective due to its unclear pathogenesis. The pathogenic role of a risk factor C-reactive protein (CRP) has been increasingly recognized in type-2 DN (T2DN). Recently, a number of studies showed that plasma CRP level can be significantly reduced in diabetic patients by dipeptidyl peptidase-4 (DPP4) inhibitor treatment. A better understanding the underlying mechanism would uncover novel therapeutic targets for ESRD.
All Author(s) ListP.M.K. Tang, Y. Zhang, J.S.C. Hung, X.R. Huang, H.Y. Lan
Name of ConferenceThe ISN World Congress of Nephrology
Start Date of Conference12/04/2019
End Date of Conference15/04/2019
Place of ConferenceMelbourne
Country/Region of ConferenceAustralia
Proceedings TitleKidney International Reports
Volume Number4
Issue NumberSupplement 7
PublisherElsevier Inc
Pages135 - 135
LanguagesEnglish-United Kingdom

Last updated on 2021-18-09 at 23:49