Dynamic Changes in Long-Term Exposure to Ambient Particulate Matter and Incidence of Hypertension in Adults
Publication in refereed journal

替代計量分析
.

其它資訊
摘要Many countries dedicated in mitigation of air pollution in the past several decades. However, little is known about how air quality improvement affects health. Therefore, we conducted current study to investigate dynamic changes in long-term exposure to ambient particulate matter (PM2.5) and incidence of hypertension in a large longitudinal cohort. We recruited 134 978 adults aged 18 years or above between 2001 and 2014. All the participants received a series of standard medical examinations, including measurements of blood pressure. The PM2.5 concentration was estimated using a satellite-based spatiotemporal model at a high resolution (1x1 km(2)). The change in long-term exposure to PM2.5 (Delta PM2.5) was defined as the difference between the values measured during follow-up and during the immediately preceding visit, and a negative value indicated an improvement in PM2.5 air quality. Time-varying Cox model was used to examine the associations between Delta PM2.5 and the development of hypertension. The results show that PM2.5 concentrations increased in 2002, 2003, and 2004, but began to decrease in 2005. Every 5 mu g/m(3) change in exposure to PM2.5 (ie, a Delta PM2.5 of 5 mu g/m(3)) was associated with a 16% change in the incidence of hypertension (hazard ratio, 0.84; 95% CI, 0.82-0.86). Both stratified and sensitivity analyses generally yielded similar results. We found that an improvement in PM2.5 exposure is associated with a decreased incidence of hypertension. Our findings demonstrate that air pollution mitigation is an effective strategy to reduce the risk of cardiovascular disease.
著者Yacong Bo, Cui Guo, Changqing Lin, Ly-yun Chang, Ta-Chien Chan, Bo Huang, Kam-Pui Lee, Tony Tam, Alexis K.H. Lau, Xiang Qian Lao, Eng-Kiong Yeoh
期刊名稱Hypertension
出版年份2019
月份9
卷號74
期次3
出版社NLM (Medline)
頁次669 - 677
國際標準期刊號0194-911X
電子國際標準期刊號1524-4563
語言英式英語
關鍵詞blood pressure, hypertension, risk, particulate matter, quality improvement

上次更新時間 2020-09-08 於 01:57