Sleep in posttraumatic stress disorder: A systematic review and meta-analysis of polysomnographic findings
Publication in refereed journal

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摘要Polysomnographic studies have been performed to examine sleep abnormalities in posttraumatic stress disorder (PTSD), but clear associations between PTSD and sleep disturbances have not been established. A systematic review of the evidence examining the polysomnographic changes in PTSD patients compared with controls was conducted using MEDLINE, EMBASE, All EBM databases, PsycINFO, and CINAHL databases. Meta-analysis was undertaken where possible. The searches identified 34 studies, 31 of which were appropriate for meta-analysis. Pooled results indicated decreased total sleep time, slow wave sleep and sleep efficiency, and increased wake time after sleep onset in PTSD patients compared with healthy controls. PTSD severity was associated with decreased sleep efficiency and slow wave sleep percentage. Rapid eye movement (REM) sleep percentage was significantly decreased in PTSD patients compared with controls in studies including participants with mean age below 30 y, but not in studies with other mean age groups (30–40 y and >40 y). Our study shows that polysomnographic abnormalities are present in PTSD. Sex, age, PTSD severity, type of controls, medication status, adaptation night, polysomnographic scoring rules and study location are several of the demographic, clinical and methodological factors that contribute to heterogeneity between studies.
出版社接受日期08.08.2019
著者Zhang Y, Ren R, Sanford LD, Yang L, Zhou J, Zhang J, Wing YK, Shi J, Lu L, Tang X
期刊名稱Sleep Medicine Reviews
出版年份2019
月份12
卷號48
文章號碼101210
國際標準期刊號1087-0792
電子國際標準期刊號1532-2955
語言美式英語

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