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> Emeritus Professor Hsiao Chang CHAN
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Professor HWE CHAN Hsiao Chang
Personal Information
Position and Department
Emeritus Professor
,
School of Biomedical Sciences
CUHK Research Outputs
1 of 6
β-Defensin 19/119 mediates sperm chemotaxis and is associated with idiopathic infertility
(
2022
)
Magnesium implantation or supplementation ameliorates bone disorder in CFTR-mutant mice through an ATF4-dependent Wnt/β-catenin signaling
(
2021
)
CFTR promotes malignant glioma development via up-regulation of Akt/Bcl2-mediated anti-apoptosis pathway
(
2020
)
KDM3A and KDM4C regulate mesenchymal stromal cell senescence and bone aging via condensin-mediated heterochromatin reorganization
(
2019
)
MRP4 sustains wnt/β-catenin signaling for pregnancy, endometriosis and endometrial cancer
(
2019
)
Progenitor Cells Derived from Drain Waste Product of Open-Heart Surgery in Children
(
2019
)
Activation of the epithelial sodium channel (ENaC) leads to cytokine profile shift to pro-inflammatory in labor
(
2018
)
CD147 Induces Epithelial-to-Mesenchymal Transition by Disassembling Cellular Apoptosis Susceptibility Protein/E-Cadherin/β-Catenin Complex in Human Endometriosis
(
2018
)
CFTR mutation enhances Dishevelled degradation and results in impairment of Wnt-dependent hematopoiesis
(
2018
)
Cystic fibrosis transmembrane conductance regulator-emerging regulator of cancer
(
2018
)
Identification of an Anti-inflammation Protein, Annexin A1, in Tendon Derived Stem Cells (TDSCs) of Cystic Fibrosis Mice: A Comparative Proteomic Analysis
(
2018
)
Retinoic acid promotes stem cell differentiation and embryonic development by transcriptionally activating CFTR
(
2018
)
CCR6 is required for ligand-induced CatSper activation in human sperm
(
2017
)
CD147 regulates extrinsic apoptosis in spermatocytes by modulating NFκB signaling pathways
(
2017
)
CFTR-β-catenin interaction regulates mouse embryonic stem cell differentiation and embryonic development
(
2017
)
COPI-TRAPPII activates Rab18 and regulates its lipid droplet association
(
2017
)
Cystic fibrosis transmembrane conductance regulator mediates tenogenic differentiation of tendon-derived stem cells and tendon repair: accelerating tendon injury healing by intervening in its downstream signaling
(
2017
)
Defective CFTR leads to aberrant beta-catenin activation and kidney fibrosis
(
2017
)
Epigenetic Modification of the CCL5/CCR1/ERK Axis Enhances Glioma Targeting in Dedifferentiation-Reprogrammed BMSCs
(
2017
)
Human MSCs promotes colorectal cancer epithelial-mesenchymal transition and progression via CCL5/β-catenin/Slug pathway
(
2017
)
Huwe1 Regulates the Establishment and Maintenance of Spermatogonia by Suppressing DNA Damage Response
(
2017
)
Mammalian TRAPPIII Complex positively modulates the recruitment of Sec13/31 onto COPII vesicles
(
2017
)
Autophapy Regulates the Early Secretory Pathway Through Interaction
(
2016
)
CFTR is a potential marker for nasopharyngeal carcinoma prognosis and metastasis
(
2016
)
Defective CFTR- β-catenin interaction promotes NF-κB nuclear translocation and intestinal inflammation in cystic fibrosis
(
2016
)
Hepatitis C virus NS5A protein cooperates with phosphatidylinositol 4-kinase IIIα to induce mitochondrial fragmentation
(
2016
)
Implant-derived magnesium induces local neuronal production of CGRP to improve bone-fracture healing in rats
(
2016
)
Involvement of Cl?/HCO3 - exchanger SLC26A3 and SLC26A6 in preimplantation embryo cleavage
(
2016
)
MycN Is Critical for the Maintenance of Human Embryonic Stem Cell-Derived Neural Crest Stem Cells
(
2016
)
The Role of Beta-defensins in Sperm Chemotaxis
(
2016
)
The Role of CFTR in Spermatogenesis
(
2016
)
The Role of Epithelial Sodium Channel (ENaC) in Endometriosis
(
2016
)
Alternative splicing of the androgen receptor in polycystic ovary syndrome
(
2015
)
CD147-regulated ERK/Bcl-2 pathway in human endometriosis
(
2015
)
CFTR-regulated MAPK/NF-κ B signaling in pulmonary inflammation in thermal inhalation injury
(
2015
)
Defective CFTR-regulated granulosa cell proliferation in polycystic ovarian syndrome
(
2015
)
Down-Regulated CFTR During Aging Contributes to Benign Prostatic Hyperplasia
(
2015
)
Dynamically Regulated CFTR Expression and Its Functional Role in Cutaneous Wound Healing
(
2015
)
Epigenetic memory gained by priming with osteogenic induction medium improves osteogenesis and other properties of mesenchymal stem cells
(
2015
)
FSH regulates fat accumulation and redistribution in aging through the Gai/Ca2+/CREB pathway
(
2015
)
The cystic fibrosis transmembrane conductance regulator as a biomarker in non-small cell lung cancer
(
2015
)
Up-regulation of Bcl-2 by CD147 Through ERK Activation Results in Abnormal Cell Survival in Human Endometriosis
(
2015
)
Basigin Regulates Spermatocyte Apoptosis Through Extrinsic Apoptotic Pathway
(
2014
)
CD147 regulates Malignant Testicular Germ Cells Apoptosis/survival Through both Extrinsic and Intrinsic Apoptotic Pathways
(
2014
)
CFTR interacts with ZO-1 to regulate tight junction assembly and epithelial differentiation through the ZONAB pathway
(
2014
)
CFTR Mutation/Downregulation Induces Inflammation in Mouse Small Intestine
(
2014
)
Deficient human beta-defensin 1 underlies male infertility associated with poor sperm motility and genital tract infection
(
2014
)
Disrupted interaction between CFTR and AF-6/afadin aggravates malignant phenotypes of colon cancer
(
2014
)
Elevated expression of CD147 in patients with endometriosis and its role in regulating apoptosis and migration of human endometrial cells
(
2014
)
Emerging role of cystic fibrosis transmembrane conductance regulator as an epigenetic regulator: linking environmental cues to microRNAs
(
2014
)
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