Professor CHAN Wan Yi

CUHK Research Outputs
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Research Interest
Research Interest: The Epidemiology and Pathogenesis of Respiratory Virus Infections, especially in the paediatric population.

• Epidemiology of Respiratory virus infection in Children
• Genotyping of Rhinovirus and its association with clinical outcomes
• Birth and Case cohorts studies on rhinovirus occurrence, host immunology and outcomes

• Rhinovirus C isolation, characterization and banking
• Functional grouping of Rhinovirus C and their biological characterization
• Rhinovirus and influenza virus interference Host & Virus Infection
• Human respiratory epithelial samples genotyping (asthma related) and banking

Host and Virus Interactions
• Tissue tropism and susceptibility of Rhinovirus in human respiratory system
• Human respiratory tissues derived organoid and its interaction with respiratory viruses

Disease Pathogenesis
• Rhinovirus infection in primary human respiratory epithelial cells (asthmatic verse non-asthmatic)
• Rhinovirus C animal model establishment: From explant cultures to in vivo study

Translational and personalized medicine
• Development and validation of Nano Biosensor detection kit for bedside management & surveillance
• Inducible pluripotent stem cell (iPSC) derived lung progeny and their use in personalized medicine

Our laboratory:
We have three proactive post-doctoral research staff, two part-time experienced and dedicated Research Assistants and an energetic PhD student as the core team.

We provide opportunities for undergraduate research students to participate in mini-project in a regular basis through the Student Campus Work Scheme (OAS) and Summer Undergraduate Research Programme (OAL) intake. Since 2015, we have trained seven UG and PG students from Hong Kong, Shandong, Taipei, London and three SURP students from the University of Sussex (United Kingdom), University of Graz (Austria) and The Karolinska Institutet (Sweden).

We are running an on-going collaborative funded project with the Pulmonary Center, Boston University School of Medicine. A PDF has started her attachment in the University Medical Center-Utrecht this summer.

Current Academic and Student Support duties:
• Co-Director of the CUHK-University Medical Center Utrecht Joint Research Laboratory of Respiratory Virus & Immunobiology, Department of Paediatrics, CUHK.
• Honorary Assistant Professor, School of Public Health, the University of Hong Kong.
• Co-ordinator of the Laboratory Administration Committee, Department of Paediatrics, CUHK.
• Member of the Postgraduate Student Research Committee, Department of Paediatrics, CUHK.
• Member of the Hong Kong Children Hospital Research Committee, Department of Paediatrics, CUHK.
• Level II Advisors for the Postgraduate Students, Department of Paediatrics, CUHK.
• Member of the Female Professorial Staff Support Network, CUHK
• Project Supervisor of the Summer Undergraduate Research Programme (SURP) student, Office of Academic Link, CUHK. (2017, 2018)
• Project Supervisor of the Student Campus Work Scheme, Office of Student Affairs, CUHK (2015-2018)
• Host of the CUHK Host Family Programme, Office of Student Affairs, CUHK (2016, 2017)

International Scientific Bodies:
Prof Chan is an active full member of the American Thoracic Society (ATS) and its Assembly on Allergy, Immunology & Inflammation (AII). She participates as the member of the ATS AII 2018-19 Program Committee Member and in the ATS Early Career Professional (ECP) Working group. Prof Chan belongs to the European Respiratory Society (ERS) as an Early Career member, the European Academy of Allergy, Clinical Immunology (EAACI) as the Junior Member and the International Network for Sequencing of Respiratory Viruses (INSPIRE) as a member of the since 2017. She has recently joined the World Society for Virology (WSV) and participated as the coordinator of the Hong Kong Sector in 2018.

Local Scientific Bodies:
- Hong Kong Institute of Allergy (HKIA); and
- Hong Kong Society of Paediatric Respirology and Allergy (HKSPRA).

Last updated on 2020-24-04 at 11:08