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> Jiang MA
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Dr. MA Jiang
(No longer affiliated with CUHK)
CUHK Research Outputs
Hepatotoxicity screening and ranking of structurally different pyrrolizidine alkaloids in zebrafish
(
2023
)
Intestinal microbiota mediates redox biotransformation of pyrrolizidine alkaloids-induced acute hepatotoxicity in rats
(
2023
)
Intestinal microbiota mediates redox biotransformation of pyrrolizidine alkaloids-induced acute hepatotoxicity in rats
(
2023
)
Dietary alcohol exacerbates the hepatotoxicity induced by pyrrolizidine alkaloids: Hazard from food contamination
(
2022
)
Fasting augments pyrrolizidine alkaloid-induced hepatotoxicity
(
2022
)
Hepatotoxicity Screening and Ranking of Structurally Different Pyrrolizidine Alkaloids in Zebrafish
(
2022
)
Liquorice Extract and 18β-Glycyrrhetinic Acid Protect Against Experimental Pyrrolizidine Alkaloid-Induced Hepatotoxicity in Rats Through Inhibiting Cytochrome P450-Mediated Metabolic Activation.
(
2022
)
Nrf2-mediated liver protection by 18β-glycyrrhetinic acid against pyrrolizidine alkaloid-induced toxicity through PI3K/Akt/GSK3β pathway
(
2022
)
Blood Pyrrole–DNA Adducts Define the Early Tumorigenic Risk in Patients with Pyrrolizidine Alkaloid-Induced Liver Injury
(
2021
)
Characterization of liver injury induced by a pyrrolizidine alkaloid in rats
(
2021
)
Clinical application of pyrrole-hemoglobin adducts as a biomarker of pyrrolizidine alkaloid exposure in humans
(
2021
)
Developing urinary pyrrole–amino acid adducts as non-invasive biomarkers for identifying pyrrolizidine alkaloids-induced liver injury in human
(
2021
)
Lung injury induced by pyrrolizidine alkaloids depends on metabolism by hepatic cytochrome P450s and blood transport of reactive metabolites
(
2021
)
Metabolism-mediated cytotoxicity and genotoxicity of pyrrolizidine alkaloids
(
2021
)
Mutational signature analysis reveals widespread contribution of pyrrolizidine alkaloid exposure to human liver cancer
(
2021
)
Polyoxypregnanes as safe, potent and specific ABCB1-inhibitory pro-drugs to overcome multidrug resistance in cancer chemotherapy in vitro and in vivo
(
2021
)
Pyrrolizidine Alkaloid-Induced Hepatotoxicity Associated with the Formation of Reactive Metabolite-Derived Pyrrole–Protein Adducts
(
2021
)
The dual roles of ginsenosides in improving the anti-tumor efficiency of cyclophosphamide in mammary carcinoma mice
(
2021
)
The first evidence of pyrrolizidine alkaloid-associated human liver cancer
(
2021
)
The key role of gut–liver axis in pyrrolizidine alkaloid-induced hepatotoxicity and enterotoxicity
(
2021
)
Tu-San-Qi (Gynura japonica): the culprit behind pyrrolizidine alkaloid-induced liver injury in China.
(
2021
)
Absorption difference between hepatotoxic pyrrolizidine alkaloids and their N-oxides - Mechanism and its potential toxic impact
(
2020
)
Comprehensive investigation and risk study on pyrrolizidine alkaloid contamination in Chinese retail honey
(
2020
)
Establishment of a novel CYP3A4-transduced human hepatic sinusoidal endothelial cell model and its application in screening hepatotoxicity of pyrrolizidine alkaloids
(
2020
)
Pulmonary toxicity is a common phenomenon of toxic pyrrolizidine alkaloids
(
2020
)
Development of a two-layer transwell co-culture model for the in vitro investigation of pyrrolizidine alkaloid-induced hepatic sinusoidal damage
(
2019
)
Intestinal and hepatic biotransformation of pyrrolizidine alkaloid N-oxides to toxic pyrrolizidine alkaloids
(
2019
)
One of the culprits of hepatic sinusoidal obstruction syndrome in China - pyrrolizidine alkaloid N-oxides
(
2019
)
Pyrrole-Hemoglobin Adducts, a More Feasible Potential Biomarker of Pyrrolizidine Alkaloid Exposure
(
2019
)
Hepatotoxicity Evaluation on Foodborne Pyrrolizidine Alkaloids
(
2018
)
Investigation of association of chemical profiles with the tracheobronchial relaxant activity of Chinese medicinal herb Beimu derived from various Fritillaria species
(
2018
)
PA toxicity and potential biomarker of PA exposure for clinical use
(
2018
)
Pyrrole-protein adducts - A biomarker of pyrrolizidine alkaloid-induced hepatotoxicity
(
2018
)
Pyrrole-protein adducts, a mechanism-based biomarker of pyrrolizidine alkaloid induced hepatotoxicity
(
2018
)
The role of formation of pyrrole-ATP synthase subunit beta adduct in pyrrolizidine alkaloid-induced hepatotoxicity
(
2018
)
18beta-glycyrrhetinic acid protects against pyrrolizidine alkaloid-induced hepatotoxicity by inhibition of CYPs-mediated metabolic activation
(
2017
)
Adduct ion-targeted qualitative and quantitative analysis of polyoxypregnanes by ultra-high pressure liquid chromatography coupled with triple quadrupole mass spectrometry
(
2017
)
Biomarker development and risk assessment of P450-mediated metabolism of pyrrolizidine alkaloids induced livery injury
(
2017
)
Chronic liver injury induced by pyrrolizidine alkaloids
(
2017
)
Development of biomarkers for clinical diagnosis of pyrrolizidine alkaloid-induced liver injury
(
2017
)
Evaluation of progressive hepatotoxicity induced by chronic exposure to pyrrolizidine alkaloids
(
2017
)
First evidence of pyrrolizidine alkaloid N-oxide-induced hepatic sinusoidal obstruction syndrome in humans
(
2017
)
Investigation of Pyrrolizidine Alkaloid-Induced Pulmonary Toxicity
(
2017
)
Investigation of the Mechanism Initiating Pyrrolizidine Alkaloid-induced Pulmonary Vascular Remodeling
(
2017
)
Pyrrolizidine Alkaloid-induced Hepatotoxicity by Mitochondrial Damage
(
2017
)
Pyrrole-hemoglobin Adduct, a Potential Biomarker of Pyrrolizidine Alkaloid-induced Hepatotoxicity
(
2016
)
Transporter modulation by Chinese herbal medicines and its mediated pharmacokinetic herb–drug interactions
(
2016
)
Anti-metastatic effect and mechanisms of Wenshen Zhuanggu Formula in human breast cancer cells
(
2015
)
Double loaded self-decomposable SiO2 nanoparticles for sustained drug release
(
2015
)
Herb and Natural Product Metabolism-mediated Hepatotoxicity
(
2015
)
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