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> Emeritus Professor Hui Yao LAN
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Professor LAN Hui Yao
Personal Information
Position and Department
Emeritus Professor
,
Department of Medicine and Therapeutics
ORCiD
0000-0003-4283-9755
CUHK Research Outputs
1 of 6
Activation of the YAP/KLF5 transcriptional cascade in renal tubular cells aggravates kidney injury
(
2024
)
Circulating metabolomic markers linking diabetic kidney disease and incident cardiovascular disease in type 2 diabetes: analyses from the Hong Kong Diabetes Biobank
(
2024
)
Angiotensin II mediates hypertensive cardiac fibrosis via an Erbb4-IR-dependent mechanism
(
2023
)
DNA methylation markers for kidney function and progression of diabetic kidney disease
(
2023
)
Estrogen receptor β attenuates renal fibrosis by suppressing the transcriptional activity of Smad3
(
2023
)
Genetic and Pharmacological Inhibition of GRPR Protects Against Acute Kidney Injury via Attenuating Renal Inflammation and Necroptosis
(
2023
)
Hypermethylation of Smad7 in CD4(+) T cells is associated with the disease activity of rheumatoid arthritis
(
2023
)
Identification of a Common Variant for Coronary Heart Disease at PDE1A Contributes to Individualized Treatment Goals and Risk Stratification of Cardiovascular Complications in Chinese Patients With Type 2 Diabetes
(
2023
)
Kidney tubular transcription co-activator, Yes-associated protein 1 (YAP), controls the expression of collecting duct aquaporins and water homeostasis
(
2023
)
Macrophages mediate psoriasis via Mincle-dependent mechanism in mice
(
2023
)
Neuropeptide Y protects kidney from acute kidney injury by inactivating M1 macrophages via the Y1R-NF-KB-Mincle-dependent mechanism
(
2023
)
New Insights into Traditional Chinese Medicine in Treatment of Diabetic Nephropathy
(
2023
)
Role of C-Reactive Protein in Kidney Diseases
(
2023
)
SARS-CoV-2 N protein induced acute kidney injury in diabetic db/db mice is associated with a Mincle-dependent M1 macrophage activation
(
2023
)
SARS-CoV-2 N protein induces acute kidney injury in diabetic mice via the Smad3-Ripk3/MLKL necroptosis pathway
(
2023
)
Smad3 is essential for polarization of tumor-associated neutrophils in non-small cell lung carcinoma
(
2023
)
Smad3 Mediates Diabetic Dyslipidemia and Fatty Liver in db/db Mice by Targeting PPARδ
(
2023
)
Targeting NK-1R attenuates renal fibrosis via modulating inflammatory responses and cell fate in chronic kidney disease
(
2023
)
The long noncoding RNA Meg3 mediates TLR4-induced inflammation in experimental obstructive nephropathy
(
2023
)
Treatment with quercetin inhibits SARS-CoV-2 N protein-induced acute kidney injury by blocking Smad3-dependent G1 cell-cycle arrest
(
2023
)
Uncovering Neutrophils as Key Immune Regulators and Translating Their Potential into Next-Generation Anticancer Therapy
(
2023
)
AANG Prevents Smad3-dependent Diabetic Nephropathy by Restoring Pancreatic β-Cell Development in db/db Mice
(
2022
)
Challenges and Recent Advances in NK Cell-Targeted Immunotherapies in Solid Tumors
(
2022
)
Clinical Predictors and Long-term Impact of Acute Kidney Injury on Progression of Diabetic Kidney Disease in Chinese Patients With Type 2 Diabetes
(
2022
)
Driving role of macrophages in transition from acute kidney injury to chronic kidney disease
(
2022
)
Editorial: Immune Landscape of Kidney Pathology
(
2022
)
Editorial: Insights in renal and epithelial physiology: 2021
(
2022
)
Follistatin-like 1 (FSTL1) interacts with Wnt ligands and Frizzled receptors to enhance Wnt/β-catenin signaling in obstructed kidneys in vivo
(
2022
)
High-density lipoprotein subclasses and cardiovascular disease and mortality in type 2 diabetes: analysis from the Hong Kong Diabetes Biobank
(
2022
)
LncRNA-Dependent Mechanisms of Transforming Growth Factor-β: From Tissue Fibrosis to Cancer Progression
(
2022
)
Macrophage Migration Inhibitory Factor (MIF) as a Stress Molecule in Renal Inflammation
(
2022
)
Macrophage Rmp ameliorates myocardial infarction by modulating macrophage polarization in mice
(
2022
)
Major Adverse Cardiovascular Events and Mortality Prediction by Circulating GDF-15 in Patients with Type 2 Diabetes: A Systematic Review and Meta-Analysis
(
2022
)
Nonalbuminuric Diabetic Kidney Disease and Risk of All-Cause Mortality and Cardiovascular and Kidney Outcomes in Type 2 Diabetes: Findings From the Hong Kong Diabetes Biobank
(
2022
)
P2Y12 inhibitor clopidogrel inhibits renal fibrosis by blocking macrophage-to-myofibroblast transition
(
2022
)
P2Y12 is a Novel Druggable Target for Blocking Macrophage-Myofibroblast Transition Driven Cancer-Associated Fibroblast Formation in Lung Carcinoma
(
2022
)
Role of TGF-Beta Signaling in Beta Cell Proliferation and Function in Diabetes
(
2022
)
SARS-CoV-2 N Protein Induces Acute Kidney Injury via Smad3-Dependent G1 Cell Cycle Arrest Mechanism
(
2022
)
Self-carried nanodrug (SCND-SIS3): A targeted therapy for lung cancer with superior biocompatibility and immune boosting effects
(
2022
)
Signaling mechanisms of SARS-CoV-2 Nucleocapsid protein in viral infection, cell death and inflammation
(
2022
)
Single‐cell RNA Sequencing Identified Novel Nr4a1 + Ear2 + Anti‐Inflammatory Macrophage Phenotype under Myeloid‐TLR4 Dependent Regulation in Anti‐Glomerular Basement Membrane (GBM) Crescentic Glomerulonephritis (cGN)
(
2022
)
Single-cell RNA sequencing uncovers a neuron-like macrophage subset associated with cancer pain
(
2022
)
Smad3 deficiency improves islet-based therapy for diabetes and diabetic kidney injury by promoting β cell proliferation via the E2F3-dependent mechanism
(
2022
)
Smad3 Promotes Cancer-Associated Fibroblasts Generation via Macrophage–Myofibroblast Transition (Adv. Sci. 1/2022)
(
2022
)
Smad3 Promotes Cancer-Associated Fibroblasts Generation via Macrophage–Myofibroblast Transition
(
2022
)
Smad3 Signatures in Renal Inflammation and Fibrosis
(
2022
)
TGF-β signaling networks in the tumor microenvironment
(
2022
)
AANG: A natural compound formula for overcoming multidrug resistance via synergistic rebalancing the TGF-beta/Smad signalling in hepatocellular carcinoma
(
2021
)
Arid2-IR promotes NF-κB-mediated renal inflammation by targeting NLRC5 transcription
(
2021
)
Deletion of Smad3 protects against C-reactive protein-induced renal fibrosis and inflammation in obstructive nephropathy
(
2021
)
Most Relevant Area
Preclinical and animal studies
(
Biomedical
)
Related Area
Pharmacology and toxicology
(
Biomedical
)
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Last updated on 2024-03-09 at 16:09
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