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> Professor Sze Lok CHENG
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鄭詩樂教授
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教授
,
生物醫學學院
ORCiD
0000-0003-2345-6951
中大研究成果
1/6
Accurate identification of structural variations from cancer samples
(
2024
)
Integrative analysis reveals associations between oral microbiota dysbiosis and host genetic and epigenetic aberrations in oral cavity squamous cell carcinoma
(
2024
)
A Selective Class I HDAC Inhibitor Recovers Intratumoral Interferon Signaling to Overcome Immune-checkpoint Blockade Resistance in Hepatocellular Carcinoma
(
2023
)
Cancer-associated fibroblasts potentiate colorectal cancer progression by crosstalk of the IGF2–IGF1R and Hippo–YAP1 signaling pathways
(
2023
)
Cold-Induced Reprogramming of Subcutaneous White Adipose Tissue Assessed by Single-Cell and Single-Nucleus RNA Sequencing
(
2023
)
Compromised browning in white adipose tissue of ageing people
(
2023
)
Deciphering the cellular and molecular determinants of immunotherapy resistance in NASH-associated hepatocellular carcinoma by single-cell analysis
(
2023
)
Eliminating METTL1-mediated accumulation of PMN-MDSCs prevents hepatocellular carcinoma recurrence after radiofrequency ablation
(
2023
)
Epigenetic activation of tumoral IFNγ response and pyroptosis overcomes immunotherapy resistance in hepatocellular carcinoma
(
2023
)
Epigenetic Remodeling of Endothelial Cells underlying Immune Checkpoint Resistance in Hepatocellular Carcinoma
(
2023
)
Fibrotic immune microenvironment remodeling mediates superior anti-tumor efficacy of a nano-PD-L1 trap in hepatocellular carcinoma
(
2023
)
Hepatoma-intrinsic FADD promotes anti-tumor CD8+T cell response
(
2023
)
Investigating the Role of HDAC8 in CD4+ T Cells
(
2023
)
Isoformic PD-1-mediated immunosuppression underlies resistance to PD-1 blockade in hepatocellular carcinoma patients
(
2023
)
Meltdown of the cold tumour microenvironment: a new 'translational' approach to augment immunotherapy efficacy
(
2023
)
Myeloid-intrinsic cell cycle-related kinase drives immunosuppression to promote tumorigenesis
(
2023
)
Neuropathological signatures revealed by transcriptomic and proteomic analysis in Pten-deficient mouse models
(
2023
)
Predicting cancer immunotherapy responses through machine learning of single-cell transcriptomes
(
2023
)
Single-cell Landscape of Cancer-associated Fibroblasts in Immunotherapy Resistance of Hepatocellular Carcinoma
(
2023
)
Targeted Protein O-GlcNAcylation Using Bifunctional Small Molecules
(
2023
)
Targeting PPAR-gamma counteracts tumour adaptation to immune-checkpoint blockade in hepatocellular carcinoma
(
2023
)
The E2F1–HOXB9/PBX2–CDK6 axis drives gastric tumorigenesis and serves as a therapeutic target in gastric cancer
(
2023
)
Tumor cell-macrophage crosstalk promotes immunotherapy resistance via lipid metabolism
(
2023
)
Unveiling Immune-Microenvironment Remodeling for NASH-related hepatocellular carcinoma Immunotherapy Resistance through Single-Cell RNA Sequencing
(
2023
)
Aberrant cholesterol metabolic signaling impairs antitumor immunosurveillance through natural killer T cell dysfunction in obese liver
(
2022
)
A Selective Class I Hdac Inhibitor Recovers Intratumoral Interferon Signaling to Overcome Immune-checkpoint Blockade Resistance in Hepatocellular Carcinoma
(
2022
)
Development of alkylated hydrazides as highly potent and selective class I Histone Deacetylase inhibitors with T cell modulatory properties
(
2022
)
Epigenetic Remodeling of Endothelial Cells underlying Immune Checkpoint Resistance in Hepatocellular Carcinoma
(
2022
)
MCM6 is a critical transcriptional target of YAP to promote gastric tumorigenesis and serves as a therapeutic target
(
2022
)
Single-Hit Inactivation Drove Tumor Suppressor Genes Out of the X Chromosome during Evolution
(
2022
)
Sirtuin 7 super-enhancer drives epigenomic reprogramming in hepatocarcinogenesis
(
2022
)
Smad3 Promotes Cancer-Associated Fibroblasts Generation via Macrophage–Myofibroblast Transition (Adv. Sci. 1/2022)
(
2022
)
Smad3 Promotes Cancer-Associated Fibroblasts Generation via Macrophage–Myofibroblast Transition
(
2022
)
The mitotic regulator RCC2 promotes glucose metabolism through BACH1-dependent transcriptional upregulation of hexokinase II in glioma
(
2022
)
Tumor cells-derived lipids modulate macrophage activity to regulate immunotherapy resistance of hepatocellular carcinoma
(
2022
)
Vitamin D3 and carbamazepine protect against Clostridioides difficile infection in mice by restoring macrophage lysosome acidification
(
2022
)
Vitamin D-3 and carbamazepine protect against Clostridioides difficile infection in mice by restoring macrophage lysosome acidification
(
2022
)
A Novel Immunosuppressive Role of Cholesterol in NAFLD-associated Hepatocarcinogenesis
(
2021
)
A proof-of-concept study for the pathogenetic role of enhancer hypomethylation of MYBPHL in multiple myeloma
(
2021
)
A selective HDAC8 inhibitor potentiates antitumor immunity and efficacy of immune checkpoint blockade in hepatocellular carcinoma
(
2021
)
A selective HDAC8 inhibitor potentiates antitumor immunity and efficacy of immune checkpoint blockade in hepatocellular carcinoma
(
2021
)
Cell cycle-related kinase reprograms the liver immune microenvironment to promote cancer metastasis
(
2021
)
Chemotherapy-induced recruitment of myeloid-derived suppressor cells abrogates efficacy of immune checkpoint blockade
(
2021
)
Enhancer dysregulation of myeloid-derived suppressor cells in hepatocellular carcinoma
(
2021
)
Epigenetic restoration of intratumoral IFNγ signaling to overcome immune-checkpoint blockade resistance in hepatocellular carcinoma
(
2021
)
Immune-checkpoint therapy resistance by tumor-intrinsic evolution in hepatocellular carcinoma
(
2021
)
Improving Liver Cancer Immunotherapy By Nanoparticle-based Targeting Of The Immunosuppressive Microenvironment
(
2021
)
Liver Immune Microenvironment and Metastasis from Colorectal Cancer-Pathogenesis and Therapeutic Perspectives
(
2021
)
Multi-omic analysis suggests tumor suppressor genes evolved specific promoter features to optimize cancer resistance
(
2021
)
NOTCH3, a crucial target of miR-491-5p/miR-875-5p, promotes gastric carcinogenesis by upregulating PHLDB2 expression and activating Akt pathway
(
2021
)
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